Genomic instability in the epidermis induced by atomic bomb (A-bomb) radiation

Atomic bomb radiation studies in Japan.

Epidemiological research on radiation-induced cancer in atomic bomb survivors

The late effects of exposure to atomic bomb radiation on cancer occurrence have been evaluated by epidemiological studies on three cohorts: a cohort of atomic bomb survivors (Life Span Study; LSS), survivors exposed IN UTERO : , and children of atomic bomb survivors (F1). The risk of leukemia among the survivors increased remarkably in the early period after the bombings, especially among child...

Leukemia in Atomic Bomb

EUKEMOGENESIS induced by repeated exposures to x-ray and other forms of radiation energy has long been recognized in man and in experimental ammals.’3 The explosion of the atomic bombs in Japan exposed two large human populations to single brief but massive doses of ionizing irradiation and subsequently a marked increase in leukemia among survivors was reported.4 ‘ The present study consists of...

Monitoring exposure to atomic bomb radiation by somatic mutation.

Atomic bomb survivors are a population suitable for studying the relationship between somatic mutation and cancer risk because their exposure doses are relatively well known and their dose responses in terms of cancer risk have also been thoroughly studied. An analysis has been made of erythrocyte glycophorin A (GPA) gene mutations in 1,226 atomic bomb survivors in Hiroshima and Nagasaki. The G...

Exposure to Atomic Bomb Radiation and Age-Related Macular Degeneration in Later Life: The Hiroshima-Nagasaki Atomic Bomb Survivor Study.

PURPOSE To investigate the association between radiation exposure from the atomic bombings and the prevalence of age-related macular degeneration (AMD) among older residents of Hiroshima and Nagasaki. METHODS The Adult Health Study is a cohort study of atomic bomb survivors living in Hiroshima and Nagasaki, comprising 2153 participants who underwent examinations with retinal fundus photograph...